#2 Nia Jax defeating Asuka
Nia Jax has been built up as Asuka's biggest threat by far on the main roster. Asuka is the winner of the first-ever Women's Royal Rumble match, so she has a guaranteed title shot at WrestleMania regardless.
As for Nia Jax, if she beats Asuka, she enters Asuka's selected title match at WrestleMania, making it a triple threat. She also ends Asuka's prestigious two-plus year undefeated streak.
WWE has really built up Asuka, with her being the first-ever Women's Royal Rumble winner. It's unlikely WWE would have given her the push if they didn't have bigger plans for her. Plus, why would WWE end her streak on a B-PPV?
That's exactly what was asked about Charlotte Flair's PPV undefeated streak, and it was ended abruptly at Fastlane 2017, infuriating many fans. Hopefully, WWE learns from this mistakes and protects The Empress Of Tomorrow, keeping her streak alive. In fact, a win over Nia would build her credibility even more.
Asuka was successful against Nia Jax on two occasions, successfully defending the NXT Women's Championship against her.