#5 John Cena defeated Brock Lesnar in his return match in 2012
John Cena and Brock Lesnar both came through the ranks at OVW, WWE's then developmental territory, before becoming megastars on the main roster. Cena and Lesnar faced each other a few times at the start of their main roster careers on with the latter getting the better of the 16-time World Champion.
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Brock Lesnar's first feud upon his return to WWE in 2012 was against John Cena, who had become 'The Guy' of WWE. Cena got his first of two wins against Lesnar at Extreme Rules 2012. This was also Brock Lesnar's first match in WWE following his return to the company.
Cena then lost the WWE Championship to Brock Lesnar at SummerSlam 2014, and couldn't regain the title. Cena's second win against Lesnar came via disqualification after Seth Rollins interfered in the match at Night of Champions 2014.
#4 Goldberg has defeated Brock Lesnar twice in WWE
Goldberg and Brock Lesnar have had a few high-profile matches in WWE, the first of which came at WrestleMania 20 in 2004. The match was won by Goldberg, but it will be remembered for how fans booed both Superstars, who were both set to leave WWE after that match.
Their second encounter came in 2016, which was Goldberg's return match at Survivor Series, where Goldberg defeated Brock Lesnar again. The Beast, though, won their final match at WrestleMania 33 in 2017 to win the Universal Championship.