#2 Roman Reigns hasn't won a title on SmackDown

Roman Reigns has held a title seven times during the course of his WWE career. Yet, he's won all these titles either on RAW or while being commissioned to RAW following the brand split in 2016. He was drafted to the Red brand during the initial split and only during last year's Superstar Shake-up did he shift to Friday nights.
Despite being a full-time member of SmackDown for over a year now, The Big Dog is yet to hold a title on the Blue brand. He's had run-ins with a lot of bad guys during this time. He's had an extended storyline with Shane McMahon and Drew McIntyre, Daniel Bryan and Erick Rowan, and more recently King Corbin.
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The Big Dog had challenged Goldberg for the Universal Championship on SmackDown. But eventually, he backed out of their fight at WrestleMania 36 due to health concerns. We can expect Roman Reigns to go for a title once he makes his return.