#1 Universal Champion: Drew McIntyre
This is actually one of the hardest title changes to predict. While the match will certainly be thrilling, I don't think AJ Styles is going to defeat Seth Rollins for the Universal Championship, and beyond him, there are no obvious contenders. The Architect is set to have a long and prosperous reign.
Nevertheless, while he hasn't won a big title yet since his return to the main roster a year ago, Drew McIntyre is still someone that the people backstage are high on and is heavily featured each and every week. Rumors suggest he might be the first to feud with Seth Rollins, but that doesn't preclude him winning the title at a later date if those rumors turn out to be true.
Charlotte Flair to return and wrestle a CURRENT CHAMPION?
Unless some new NXT call up radically changes the game, Drew McIntyre is best poised to dethrone Rollins in the long run.