How to farm Runewords in Diablo 4 Vessel of Hatred

Through the Diablo 4 Vessel of Hatred story, you’ll unlock powerful Runewords. You can equip two combinations of words, which replace gems in some of your armor. These Runes are remarkably powerful, and can give your class abilities it might not have. Do you want a Rogue with War Cry? That’s certainly feasible in the Vessel of Hatred expansion. However, at first, it’s going to feel a lot like Diablo 2, as Runes will feel rare, and won’t drop often. There are some ways to mitigate that and make them a bit easier to farm.

Diablo 4 Vessel of Hatred added these powerful Runewords to the game, though more could show up in the future. If you’re looking to farm Runes, we have some tips that will make it a little easier for you.

Can you easily farm Runewords in Diablo 4 Vessel of Hatred?

Undercity is your best bet to farm Runes, if you have the right Tribute (Image via Blizzard Entertainment)

The best way to farm Runewords in Diablo 4 Vessel of Hatred is to have access to the Undercity. You’ll have the ability to unlock this content as you play through the Vessel of Hatred storyline. A series of quests in Upper Kurast will take you through all three of the current dungeon layouts in Undercity. You can farm Runes, but it's not easy unless you have the right tools for the job.

While you can get Runes almost anywhere in the Vessel of Hatred endgame activities, the best place is Undercity. This is thanks to one of the Tributes that you can unlock here. You can get Tributes in many of the end-game activities in Diablo 4, such as Helltide chests, Seething Portals and Tree of Whispers caches. You can run Undercity without them and still get Rune drops, but they won’t be as plentiful.

If you want a good quantity of Runes, you'll need the Tribute of Harmony. Part of the Undercity gimmick in Diablo 4 is that you can use Tributes to guarantee specific drops - like Runes.

Tribute of Harmony guarantees Runes in your rewards as long as you get at least Attunement Rank 1 in a run, which is incredibly easy. However, the downside is that you may have to be on Torment difficulty to use this particular Tribute. That means you really can’t farm Runes easily in D4 Vessel of Hatred.

Seething Opals can also help you get Runes, if you find the right one (Image via Blizzard Entertainment)

It’s unfortunate that there isn’t really an easier way to farm Runes in Diablo 4, unless the Tree of Whispers unveils a Rune Cache. In general, playing endgame activities is one of the most reliable ways outside of the Tribute Undercity runs. They aren’t going to show up as often, but it will also help you increase your power in general, with better gear and more resources.

There's one more option for farming Runes in D4 - Seething Opals. Seething Opals are a new type of Elixir in Season 6, and if you stumble upon Seething Opal of Socketables, you have a chance to see more Rune drops.

For a half hour, enemies will routeinely drop additional Gem Fragments, and occasionally Runes. This lets you go anywhere, and kill massive swarms of enemies for a shot at more Runewords.

All Runewords available in Diablo 4 Vessel of Hatred

Completing Firmament of the Faith will net you a few Runes - the others you have to farm on your own (Image via Blizzard Entertainment)

As of Diablo 4 Vessel of Hatred, a wealth of Runewords were added to the game. Their actual rarity seems to vary wildly - though the most powerful Runewords, such as Lith feeling very hard to come by.

It's worth noting that you can find these in other places too, such as trading with other players, and purchasing them with gold on third-party websites - but we do recommend caution, because there are scammers who will try to leave you high and dry. If you want to know all Runes in Diablo 4 Vessel of Hatred, you can see that list below.

Runes of Ritual

Yul, Legendary:
Gain: 50 Offering.
Cast a Skill with a Cooldown.
Cir, Magic:
Gain: 25 Offering.
Cast the same non-Channeled Skill 3 times in a row.
Ahu, Legendary:
Gain: 10 Offering.
Lucky Hit: Up to a 100% chance against Injured enemies.
Neo, Rare:
Gain: 300 Offering.
Deal damage after not taking any within 5 seconds. (Resets if Invulnerable.)
Tam, Legendary:
Gain: 25 Offering.
Cast a non-Channeled Core Skill.
Xol, Legendary:
Gain: 150 Offering.
Evoke power from another Class.
Zan, Magic:
Gain: 150 Offering.
Cast an Ultimate Skill.
Feo, Rare:
Gain: 1000 Offering.
Become Injured or Crowd Controlled (Cooldown: 20 seconds).
Noc, Rare:
Gain: 5 Offering.
Inflict a Crowd Control that isn't Slow or Chill.
Cem, Magic:
Gain: 50 Offering.
Cast Evade.
Bac, Legendary:
Gain: 50 Offering.
Travel 5 meters.
Ur, Magic:
Gain: 10 Offering.
Your Minion or Companion kills an enemy or dies.
Yax, Magic:
Gain: 100 Offering.
Drink a Healing Potion.
Poc, Rare:
Gain: 2 Offering.
Spend 5% of your Maximum Resource.
Moni, Magic:
Gain: 10 Offering.
Cast a Skill after moving. (Cooldown: 0.2 seconds)
Kaa, Rare:
Gain: 2 Offering.
Lose 1% of your Maximum Life.
Lith, Legendary:
Gain: 25 Offering.
Stand still for 0.3 seconds.

Runes of Invocation

Lac, Rare:
Requires: 800 Offering (Overflow: Increased Duration). Cooldown: 1 Second.
Evoke the Barbarian's Challenging Shout, reducing your damage taken.
Ohm, Legendary:
Requires: 500 Offering (Overflow: Increased Duration). Cooldown: 2 Seconds.
Evoke the Barbarian's Enhanced War Cry, increasing your Movement Speed and damage dealt.
Vex, Legendary:
Requires: 400 Offering (Overflow: Increased Duration). Cooldown: 1 Second.
Gain +3 to all Skills for 5 seconds.
Gar, Magic:
Requires: 25 Offering (Overflow: Gain Multiple Stacks). Cooldown: 1 Second.
Gain 2.5% Critical Strike Chance for 5 seconds, up to 25%.
Xan, Legendary:
Requires: 700 Offering Cooldown: 1 Second.
Your next Skill cast will be a guaranteed Critical Strike and Overpower.
Que, Rare:
Requires: 800 Offering (Overflow: Increased Duration) Cooldown: 1 second.
Evoke the Druid's Earthen Bulwark, granting yourself a Barrier.
Yom, Legendary: Requires:
500 Offering Cooldown: 5 Seconds.
Evoke the Druid's Petrify, Stunning enemies and increasing your Critical Strike Damage against them.
Eom, Legendary:
Requires: 100 Offering (Overflow: Further Reduced Cooldowns) Cooldown: 1 Second.
Reduce your active Cooldowns by 0.25 seconds.
Lum, Magic:
Requires: 5 Offering (Overflow: Increased Resource Restored) Cooldown: 1 Second.
Restore 1 Primary Resource.
Qua, Rare: Requires:
400 Offering (Overflow: Increased Duration) Cooldown: 1 Second.
Restore an Evade charge and gain 6% Movement Speed for 5 seconds, up to 30%.
Xal, Rare:
Requires: 200 Offering (Overflow: Increased Duration) Cooldown: 1 Second.
Gain 20% Maximum Life for 4 seconds.
Wat, Rare:
Requires: 100 Offering Cooldown: 1 Second.
Evoke the Necromancer's Horrid Decrepify, Slowing enemies, reducing their damage, and letting you Execute them.
Teb, Magic:
Requires: 100 Offering Cooldown: 1 Second.
Evoke the Necromancer's Abhorrent Iron Maiden, counterattacking damage from enemies and Healing you when they die.
Qax, Rare:
Requires: 400 Offering (Overflow: Further Increased Damage) Cooldown: 1 Second.
Your next non-Basic Skill cast spends all of your Primary Resource to deal up to 100% increased damage.
Zec, Rare:
Requires: 200 Offering (Overflow: Further Reduced Cooldown) Cooldown: 2 Seconds.
Reduce your active Ultimate Cooldown by 4 seconds.
Ner, Rare:
Requires: 700 Offering (Overflow: Increased Duration) Cooldown: 6 Seconds.
Evoke the Rogue's Countering Concealment, gaining Dodge Chance, Movement Speed, Unstoppable, and Stealth.
Mot, Rare:
Requires: 150 Offering (Overflow: Gain Multiple Shadows) Cooldown: 1 Second.
Gain a shadow from the Rogue's Dark Shroud, reducing damage taken per shadow.
Jah, Legendary:
Requires: 500 Offering Cooldown: 2 Seconds.
Replace your next Evade with the Sorcerer's Teleport, blinking further, dealing damage, and becoming Unstoppable.
Thul, Rare:
Requires: 400 Offering (Overflow: Increased Size) Cooldown: 1 Second.
Evoke the Sorcerer's Mystical Frost Nova, inflicting Freeze and Vulnerable onto enemies.
Tzic, Rare:
Requires: 250 Offering Cooldown: 1 Second.
Evoke the Spiritborn's Concussive Stomp, dealing damage and Knocking Down enemies.
Kry, Rare:
Requires: 500 Offering Cooldown: 3 Seconds.
Evoke the Spiritborn's Vortex, dealing damage and Pulling In enemies.
Ono, Magic:
Requires: 25 Offering (Overflow: Increased Bolts Spawned) Cooldown: 1 Second.
Evoke the Druid's Dancing Bolts, seeking and dealing damage to enemies.
Tec, Magic:
Requires: 100 Offering (Overflow: Increased Size) Cooldown: 1 Second.
Evoke the Barbarian's Earthquake, dealing damage to enemies within.
Met, Magic:
Requires: 100 Offering (Overflow: Increased Duration) Cooldown: 1 Second.
You leave the Necromancer's Desecrated Ground behind you for 3 seconds, dealing damage to enemies within.
Tun, Magic:
Requires: 100 Offering (Overflow: Increased Grenades Spawned) Cooldown: 1 Second.
Evoke the Rogue's Stun Grenades, Stunning and dealing damage to enemies.
Ton, Magic:
Requires: 25 Offering (Overflow: Increased Meteorites Spawned) Cooldown: 1 Second.
Evoke the Sorcerer's Meteorites, dealing damage to enemies.
Tal, Magic:
Requires: 100 Offering (Overflow: Increased Swarms Spawned) Cooldown: 1 Second.
Evoke the Spiritborn's Pestilent Swarm, dealing damage to enemies.
Ceh, Magic:
Requires: 100 Offering (Overflow: Summon Multiple Wolves) Cooldown: 1 Second.
Summon a Spirit Wolf to attack enemies for 8 seconds.

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Edited by Ripunjay Gaba