8 Best Endgame Uniques in Last Epoch

Best Endgame Uniques in Last Epoch
Best Endgame Uniques in Last Epoch (Image via Eleventh Hour Games)

When it comes to Last Epoch's endgame, theory-crafting and min-maxing your build take center stage, and nothing defines a build more than the perfect Unique item. While crafted exalted gear holds incredible power, certain Uniques are so impactful that they become essential for pushing into top-tier content.

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With the arrival of Season 2: Tombs of the Erased, several new Uniques have stirred up the meta, yet many fan-favorites from the previous season continue to dominate the high-tier scenarios.

In this guide, we will break down the 8 best endgame Uniques in Last Epoch, ranked by their ability to enable builds, cross-class utility, and overall relevance in your late-game progression.

Disclaimer: The views and rankings presented here are based on my gameplay experience and analysis. Item performance may vary depending on future patches, balance changes, and personal build preferences.

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Also Read: 6 Best Leveling Uniques in Last Epoch


8 Best Build-Enabling Uniques Worth Chasing in Last Epoch

8) Wings of Argentus (Body Armor)

Wings of Argentus, Unique Body Armor (Image via Eleventh Hour Games)
Wings of Argentus, Unique Body Armor (Image via Eleventh Hour Games)

Wings of Argentus remains a staple for melee elemental builds, offering a chance to gain Haste on hit and reduced damage taken while moving. This chest piece is a fantastic choice for characters that rely on high mobility and sustained movement-based defenses.

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Why it’s ranked #8:

While it is a strong defensive item for mobile builds, it requires constant motion to unlock its full potential. Hence, it falls short for stationary playstyles, channeling skills, or characters that don't prioritize moving so much.

How to Obtain:

  • Drops from God Hunter Argentus (Empowered The Stolen Lance Timeline) — up to 45% chance with increased item rarity.

7) Falcon Fists (Gloves)

Falcon Fists Unique Gloves (Image via Eleventh Hour Games)
Falcon Fists Unique Gloves (Image via Eleventh Hour Games)

Falcon Fists, crafted specifically for Falconers, unlock a unique unarmed melee combat style. Tied heavily to skills like Dive Bomb and Shift, it offers faster attack speeds and devastating burst potential.

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Why it’s ranked #7:

It is extremely powerful within Falconer builds but practically useless outside that mastery, making its applications quite niche.

How to Obtain:

  • Random drop (common)
  • 5.39% chance from using Rune of Ascendance
  • Available via "Unique or Set Gloves" rewards in the Ending the Storm Timeline

6) Aurora’s Time Glass (Amulet)

Aurora's Time Glass Unique Amulet (Image via Eleventh Hour Games)
Aurora's Time Glass Unique Amulet (Image via Eleventh Hour Games)

This amulet acts as a panic switch, instantly rewinding your health once it drops below a critical threshold. In Monolith boss fights or high corruption echoes, where one mistake can be fatal, Aurora’s Time Glass shines.

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Why it’s ranked #6:

It offers fantastic survivability, especially for Hardcore players. However, it provides no offensive value and won't help speed up clear times.

How to Obtain:

  • Random drop (very rare)
  • 1.42% chance to get by using Rune of Ascendance
  • Found in The Age of Winter Timeline under "Unique or Set Amulet" echoes

5) Death Rattle (Amulet)

Death Rattle Unique Amulet (Image via Eleventh Hour Games)
Death Rattle Unique Amulet (Image via Eleventh Hour Games)

Death Rattle is necessary for critical strike minion builds. It allows your summons to land critical hits and grants them massive critical damage multipliers, pushing minion DPS into another tier.

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Why it’s ranked #5:

This Unique is essential for crit minion builds but useless outside of summoner-focused build setups.

How to Obtain:

  • Random drop (common)
  • 7.1% chance to get by using Rune of Ascendance
  • Available in The Age of Winter Timeline ("Unique or Set Amulet" echoes)

4) Exsanguinous (Body Armor) + Twisted Heart of Uhkeiros (Relic)

Exsanguinous Unique Body Armor + Twisted Heart of Uhkeiros Unique Relic (Image via Eleventh Hour Games)
Exsanguinous Unique Body Armor + Twisted Heart of Uhkeiros Unique Relic (Image via Eleventh Hour Games)

When combined, these two Uniques define low life ward builds. Exsanguinous steadily drains your HP, converting it into a ward, while Twisted Heart boosts your ward further every time you spend mana, creating some of the tankiest builds without needing top-end exalted gear.

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Why it’s ranked #4:

Requires very thoughtful planning to maximize its overall effectiveness. This setup is not a simple plug-and-play, but needs to be properly built around for it to provide S-tier defenses.

Exsanguinous (Body Armor) - How to Obtain:

  • Random drop (rare)
  • 3.17% chance to get by using Rune of Ascendance
  • Found in Blood, Frost, and Death Timeline ("Unique or Set Body Armor" echoes)

Twisted Heart of Uhkeiros (Relic) - How to Obtain:

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  • Drops from Emperor of Corpses (Reign of Dragons Timeline) — 6% chance (up to 48% with increased item rarity)

3) Omnis (Amulet)

Omnis Unique Amulet (Image via Eleventh Hour Games)
Omnis Unique Amulet (Image via Eleventh Hour Games)

Omnis remains one of the ultimate Uniques, offering +1 to all skills, significant resistance boosts across the board, and critical chance bonuses. It solves numerous gearing headaches, especially where you are lacking resistances.

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Why it’s ranked #3:

A near-universal best-in-slot item, but its extreme rarity (only dropping in high-corruption echoes) makes it tough to acquire.

How to Obtain:

  • Drops from Shade of Orobyss (minimum 200 corruption) — 15% chance
  • Confluence of Oblivion Woven Echo — 35% chance (higher odds with increased corruption and distance from the center)

2) Omnividence (Two-Handed Staff)

Omniviidence Unique Two-handed Staff (Image via Eleventh Hour Games)
Omniviidence Unique Two-handed Staff (Image via Eleventh Hour Games)

Omnividence is an absolute powerhouse for Void spellcasters. It offers massive base spell damage, Intelligence scaling, Void synergy, and damage reflection, enabling it to dish out unparalleled DPS spikes for classes like Warlock and Void Knight.

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Why it’s ranked #2:

The Omnividence is incredibly strong for Void spellcasters, but its benefits don't extend outside that particular niche.

How to Obtain:

  • Random drop (very rare)
  • 1.16% chance to get by using Rune of Ascendance
  • Available via "Unique or Set Staff or Sceptre" echoes in The Stolen Lance Timeline

1) Sigeon’s Reprisal (Shield)

Sigeon's Reprisal Unique Shield (Image via Eleventh Hour Games)
Sigeon's Reprisal Unique Shield (Image via Eleventh Hour Games)

Sigeon’s Reprisal redefines the archetype of retaliation builds in Last Epoch. By having damage on block mechanics, it transforms pure defense into a devastating offensive weapon, perfectly suited for Paladins and Forge Guards.

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Why it’s ranked #1:

The Item does more than just enhance existing archetypes; it spawns entirely new playstyles, making it one of the most important Uniques added recently.

How to Obtain:

  • Random drop (common)
  • 7.81% chance to get by using Rune of Ascendance
  • Available via "Unique or Set Shield" echoes in The Black Sun Timeline

Honorable Mentions

  • Spine of Malatros (Two-Handed Sword): It's a Warlock-exclusive sword that converts Chthonic Fissure into summoning Flame Whips, making it perfect for specific flame-based builds.
  • Communion of the Erased (Belt): It doubles the belt’s stats after using a potion, excellent when paired with Weaver’s Will items, but requires potion-based setups.
  • Vial of Volatile Ice (Catalyst): Converts Acid Flask into a Frostbite-stacking AoE, making it particularly powerful for cold-based builds in Last Epoch.
  • Wings of Argentus (Body Armor): Best suited for high-mobility melee elemental builds; offers massive boosts to Melee Fire and Cold damage.
  • Ravenous Void (Gloves): Grants phases of invulnerability when hit and remains powerful defensively, but demands careful resource management to survive mimic damage.
  • Red Ring of Atlaria (Ring): Provides boosts to all Attributes, causing you to take significantly less damage, while giving significant regen to Health, Mana, and Dodge Rating.
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Last Epoch’s endgame landscape will continue to evolve, but certain Uniques consistently stand above the rest, not just by amplifying existing builds, but by unlocking entirely new styles of play.

Whether your goal is to survive the hardest Monolith bosses, obliterate enemies at lightning speed, or experiment with creative new builds, hunting down these powerful Uniques will take your endgame journey to a whole new level.

Good luck, and may your echoes bring fortune!

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Check out our other guides on Last Epoch:

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Edited by Shraman Mitra
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