Once Human Specialization tier list

Specializations in Once Human are perks that players acquire through Memetics every five levels, starting at Level 5, with the final one unlocking at the max character level of 50. At each of these levels, you can choose one of four random Specializations, which provide significant bonuses or facility/item blueprints to aid you in your journey through this post-apocalyptic world.

Changing Specializations in Once Human is quite challenging, as the items required to reroll them are either available in limited quantities per phase or are rare drops that are difficult to obtain. So, selecting the best ones as you level up becomes quite essential to your progression in the game.

Note: Some aspects of this article are subjective and solely reflect the writer's opinion.

Memetic Specialization tier list for Once Human: All perks ranked

S-Tier

The Red Plasma Missiles are essential in defeating the Nightmare Prime War boss, Manibus (Image via Starry Studio)

The Specializations in this tier are highly valuable in the endgame and can be game-changing in certain situations. They are the best perks you can acquire if you get lucky with the RNG.

That said, some of these perks provide facility upgrades that are one-and-done, meaning you can place the upgraded facility at your base and use it for the rest of the game without requiring the Specialization anymore. But, you can still capitalize on the high demand for these facilities by placing them at other players' bases in exchange for resources, items, or currency.

These are the S-Tier Specializations in Once Human:

Specializations	Levels
Furnace: Precision Refining	5, 10, 15
Super Refinery	5, 10, 15
Disassembly Bench: Careful Disassembly	5, 10, 15
Disassembly Bench: Electronic Recycling	5, 10, 15
Supplies Workbench: Ammo Factory	5, 10, 15
Gear Workbench: Customization	5, 10, 15
Supplies Workbench: Healing Boost	20, 25, 30
Supplies Workbench: Anti-Armor	40, 45, 50
Biomass Missile: Ample Munition	20, 25, 30
Oil Processing	20, 25, 30
Sulfur Chemist	20, 25, 30
Generator Electrical Expert	20, 25, 30
Deviant Power Generator: Stardust Unleased	40, 45, 50
Hydraulic Generator: One with the Tides	40, 45, 50
Electric Furnace: Electrolysis	40, 45, 50
Kitchen Set: Gourmand	40, 45, 50
Red Plasma Rounds	40, 45, 50

A-Tier

The Electronics Grabber is a very useful item (Image via Starry Studio)

The A-Tier Specializations in Once Human can be nearly as useful as the S-Tier ones, but the items or facilities they provide are often available for purchase from other players at a relatively low cost.

Similar to the S-Tier perks, they are also one-and-done. So, if you have to choose between an S or A-Tier perk, it's generally better to go for the former and buy the A-Tier benefits instead.

Here are the A-Tier Specializations in Once Human:

Specializations	Levels
Backpack Expansion	5, 10, 15
Electronics Grabber	5, 10, 15
Gravel and Log On-the-Go	5, 10, 15
Custom Storage Crate	5, 10, 15
Chef's Knife	5, 10, 15
Harvesting Sickle	5, 10, 15
Gardening Gloves	5, 10, 15
Canned Goods: Mini Canner	20, 25, 30
Iced Treat: Brain Freeze	20, 25, 30
Biomass Generator: Sustained Output	20, 25, 30
Stardust Mining Platform	40, 45, 50
Combo Chipset	20, 25, 30
Precious Metal Refining	20, 25, 30
Solar Drill	20, 25, 30
Electric Drill: Treasure Hunter	20, 25, 30
Portable Fridge	20, 25, 30

Also Read: Once Human weapons tier list

B-Tier

You can purchase the Compost Bin from a player (Image via Starry Studio)

The B-Tier Specializations in Once Human allows you to craft some good quality-of-life items and facilities, but they are not essential or game-changing. These perks are worth picking if there aren't any better options available or if you have already acquired the higher-tier items and only need these remaining ones.

The following are the B-Tier Specializations:

Specializations	Levels
Compost Bin	5, 10, 15
Stove: Long-Term Storage	5, 10, 15
Portable Rainwater Collection System	5, 10, 15
Stone Structures: Intense Defense	20, 25, 30
Improved Compound Fertilizer	20, 25, 30
Furnace: Sintering	20, 25, 30
Electric Furnace: Efficiency Lover	20, 25, 30
Portable MG Turret: Barrage of Bullets	20, 25, 30
Solar Generator: Photon Power	20, 25, 30
Stardust Water Pump	20, 25, 30
Adrenaline Shot: Phoenix	20, 25, 30
Scout Drone: Invisible Hunter	40, 45, 50
Stardust Regulator	40, 45, 50
Stardust Barrier: Hold the Line	40, 45, 50
Stardust Dish: Shell Break	40, 45, 50
Crystal Transformation	40, 45, 50
Rare Crystal Set	40, 45, 50
Art of Stardust Decay	40, 45, 50
Lucky Logging Platform	40, 45, 50

C-Tier

The Specializations in this tier might be useful in specific niche scenarios, but their bonuses are mostly ineffective and only help add some flavor to your gameplay.

The C-Tier Specializations are the following:

Specializations	Levels
Pickaxe: Moonlight Mining	5, 10, 15
Pickaxe: Forest Foe	5, 10, 15
Explosive Sack	5, 10, 15
Throwing Dagger: Bullseye	5, 10, 15
Activated Carbon Filter	5, 10, 15
Portable Diving Gear	5, 10, 15
Roasted & Dried: Low and Slow	5, 10, 15
Wood Structures: Tough Plant	5, 10, 15
Basic Defense: Battle-Hardened	5, 10, 15
Flamethrower Trap: Scorching Blast	5, 10, 15
Robotics Facility: Skilled Mechanician	5, 10, 15
Explosive On-the-Go	5, 10, 15
Jump Booster	5, 10, 15
Bed: A Place to Call Home	5, 10, 15
Chainsaw: Chainsaw Horror Show	20, 25, 30
Portable Updraft Cannon	20, 25, 30
Synthesis Bench: Recycle & Reuse	20, 25, 30
Updraft Cannon: Gravity Lite	20, 25, 30
Gravitational Grip: Bonds of Guidance	20, 25, 30
Shotgun Turret: Volley Fire	20, 25, 30
Explosive Throwables: Echo Blast	20, 25, 30
Claymore Mine: Warrior's Resolve	20, 25, 30
Spectral Cloak	40, 45, 50
Gold Pickaxe and Silver Pickaxe	40, 45, 50
Reinforced Structures: Healing Defense	40, 45, 50
Nalcott Easter Egg	40, 45, 50
Gold Knife	40, 45, 50
Gatling Cannon: Power Blast	40, 45, 50
High Power Rocket Warhead	40, 45, 50
Ultra Grenade	40, 45, 50
Lightning Impulse Regulator	40, 45, 50
Rifle Turret: Two Birds One Stone	40, 45, 50

Check out our other guides on this game:

Edited by Ashmita Bhatt