Coda Pox is not remotely the most performant Coda weapon in Warframe, but it can certainly be Steel Path-viable with the right build. Same as the regular Pox, this thrown secondary can be written off as a pocket Torid (without the Incarnon glow-up). It involves the same poison-cloud mechanic, and thanks to the new Secondary Enervate Arcane, it has some unexpectedly strong interactions with DoT procs.
On the whole, the only serviceable way to build Coda Pox in Warframe is by utilizing its group-damage potential.
A good Coda Sporothrix build only pops off with group-up Warframes

Pox's central gimmick is a toxic cloud that can deal group damage in an admittedly small area. Successful hits on an enemy will create a DoT cloud that deals damage and applies crits and status separately from the weapon. This is calculated when the cloud is created, so if you had a buff that expired after the creation of the cloud, it will still inherit the boosted stats for the full duration.
Without the cloud, the Coda Pox is otherwise a very middling thrown secondary — a weapon type that doesn't see wide usage otherwise. In other words, to get the juice out of Coda Pox, you must run some sort of enemy grouping tool. This can be done with a Helminth or an innate ability such as Ensnare or Coil Horizon, or just by running Nautilus as your companion.
Warframe Coda Sporothrix build for endgame (5-Forma)

Since it's a Coda weapon, you'll need 5 Formas to extract all the Mastery out of it in any case. So with this build, we'll try to also leverage the Coda Pox's only good talent as discussed before: the cloud.
Since we are trying to group enemies, Blast is the Element of choice. For this, you'll want to get a Cold Progenitor so you can run a Primed Heated Charge on it to create Blast. This also gives you the option to swap two mods to go for Viral-Gas. Here are the mods and the arcane used for this build:
Mods
- Hornet Strike (V Forma)
- Pistol Elementalist (D Forma)
- Pistol Pestilence
- Jolt
- Galvanized Diffusion (V Forma)
- Primed Heated Charge (Dash Forma)
- Primed Fulmination (Use Frostbite here if using Magnetic progenitor)
- Primed Target Cracker (V Forma)
Arcane
Secondary Enervate is the bread-and-butter of this build.
As we mentioned before, Coda Pox's cloud inherits the stats at the time of proccing. In other words, you can snapshot the cloud at maximum Enervate Stacks before it resets, to get some quite funny red crit numbers. This is not a useable combo in the average mission, but it does breathe some life into an otherwise disappointing Coda weapon.
Check out our other guides on the game:
- All Warframes tier list
- Warframe Incarnon weapons tier list
- Warframe Kuva weapons tier list
- Warframe Coda weapons tier list
- Best weapons in Warframe for each Mastery Rank