Knowledge of Damage rotation is necessary when venturing into Destiny 2's ultra-endgame. The term refers to a combination of weapons a player can use to damage a boss. 'Optimal damage rotation' should always include three weapons that add up the most damage against a Raid or a Dungeon boss. For seven years, the game has had different rotations throughout countless sandbox changes.
This article goes through the best damage rotation in Episode Heresy and the safest option to use in the endgame until the Edge of Fate expansion. Additionally, with challenging Dungeons scheduled for Rite of the Nine, it is recommended that everyone has a damage rotation ready in their build.
Note: This article will mention the best damage rotation for 6-player fireteams.
Required Artifact perks in Destiny 2 Heresy for optimal damage rotation
The damage rotation mentioned in this article features the new and improved Hezen Vengeance Rocket Launcher from Vault of Glass. Due to this, we recommend getting the "Legend Incarnate" perk from the Heresy Artifact.

This perk passively grants bonus damage to all Vault of Glass weapons alongside Overcharge while the modifier is active. Gold from Lead can be a great perk between damage phases for ammo, with Horde Shuttle and To Shreds. Horde Shuttle will spawn Threadling against Unraveled, leading to more damage against a single target.

You can Unravel a boss with an Arcane Needle from any Strand/Prismatic Warlock in the fireteam.
For To Shreds, anyone in your party can have a primary weapon with the Slice perk to apply the Sever debuff.
Required weapons for the best damage rotation in Destiny 2 Heresy
The best damage rotation in Episode Heresy can be achieved with a Bait-and-Switch/Envious Arsenal Hezen Vengeance Rocket Launcher, an Assault Mag Precision Slug Shotgun, and a Witherhoard Exotic Grenade Launcher.
One member in your fireteam must use Gjallarhorn to trigger the Hezen's Wolfpack Rounds, and another member must juggle between weakening the boss with Tractor Cannon and damage.

The rotation with Hezen will be like this:
- Start damaging with Witherhoard for continuous DoT.
- Switch to your precision Slug to damage the boss, triggering the Hezen's Bait-and-Switch damage buff, and the Envious Arsenal's auto-reload.
- Rain down Hezen Vengeance with the active 'Wolfpack Rounds' from your fireteam's Gjallarhorn.
- Repeat the rotation.
Check out our other Destiny 2 articles:
- All Exotic weapon changes in Heresy Act I
- Imminence god roll guide
- Episode Heresy weekly reset
- Essence of Desire farming guide
- Best ways to heal in The Nether
- Easiest way to get the Queenbreaker Catalyst
- Derealize Exotic mission guide
- How to get the Barrow-Dyad quest