4) Frank Gore
![Chargers v 49ers - Source: Getty](https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=190 190w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=720 720w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=640 640w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=1045 1045w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=1200 1200w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=1460 1460w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg?w=1600 1600w, https://staticg.sportskeeda.com/editor/2025/02/57ec4-17389103802178-1920.jpg 1920w)
When Frank Gore retired after the 2020 season, he did so as one of the most durable running backs in NFL history, having played a record 241 games. The man seemingly refused to age, continuing to be capable of strong performances well into his 30s.
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![march madness logo](http://staticg.sportskeeda.com/skm/assets/march-madness-logo.png)
He was a critical component of the San Francisco 49ers' 2010s return to contention after an extented time in the doldrums, and holds the franchise's all-time rushing yards record.
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Edited by Bhargav