Wednesday, September 21, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS |
| Darren Hall | CB | 21-9 | Knee | Questionable for Week 3 at Seattle |
Sunday, September 18, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS |
| Cornell Armstrong | DB | 18-9 | Undisclosed | Questionable for Week 3 at Seattle |
Saturday, September 17, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS | EXPECTED RETURN |
| Damien Williams | RB | 17-9 | Ribs | IR. Injured Reserve | Week 6 |
Friday, September 16, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS | EXPECTED RETURN |
| Jalen Mayfield | OT | 16-9 | Back | IR. Injured Reserve | Week 5 |
Wednesday, September 14, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS |
| Beau Brinkley | LS | 14-9 | Undisclosed | IR. Injured Reserve |
Sunday, September 11, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS | EXPECTED RETURN |
| Deion Jones | LB | 11-9 | Shoulder | IR. Injured Reserve | Week 5 |
Friday, September 9, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS | EXPECTED RETURN |
| Marlon Davidson | DE | 9-9 | Knee | IR. Injured Reserve | Week 5 |
Friday, September 2, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS |
| Vincent Taylor | DT | 2-9 | Achilles | IR. Injured Reserve |
Thursday, September 1, 2022
| PLAYER | POSITION | UPDATED | INJURY | INJURY STATUS | EXPECTED RETURN |
| Isaiah Oliver | DB | 1-9 | Knee | IR. Injured Reserve | Week 5 |
| John FitzPatrick | TE | Thu, Sep 1 | Undisclosed | IR. Injured Reserve | Week 5 |
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