The struggling Carolina Panthers will travel to Orchard Park to take on the Buffalo Bills on Sunday.
The Panthers are at the bottom of the AFC South standings with a 5-8 record and defeat on Sunday will ensure they finish the season with a losing record.
The Bills' hopes of defending their AFC East crown were given a new lease of life by the Indianapolis Colts, who beat the New England Patriots on Saturday. The Bills cannot afford a slip if they hope to retain their division title.
Here's the injury report and starting lineup for the Bills and Panthers:
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Buffalo Bills vs. Carolina Panthers injury report
Buffalo Bills injury report
Wide receiver Emmanuel Sanders is a huge doubt for the game against the Panthers on Sunday due to a knee injury.
The Bills have listed three other players as questionable to play on Sunday: running back Taiwan Jones (knee), defensive tackle Star Lotulelei (toe) and defensive end A.J. Epenesa (ankle).
All three were limited participants in practice and are expected to suit up on Sunday.
Carolina Panthers injury report
The Panthers' secondary won't have the services of cornerback A.J. Bouye, who is out with a foot injury.
Three other Carolina players could miss the game against the Bills: Wide receiver DJ Moore, guards Michael Jordan and John Miller.
Buffalo Bills vs. Carolina Panthers starting lineup
Buffalo Bills
QB - Josh Allen | RB - Devin Singletary | WR - Stefon Diggs, Isaiah McKenzie, Cole Beasley | TE - Dawson Knox | OL - Spencer Brown, Jon Feliciano, Mitch Morse, Daryl Williams, Tommy Doyle
DL - Greg Rousseau, Ed Oliver, Star Lotulelei, Jerry Hughes | LB - Matt Milano, Tremaine Edwards, A.J. Klein | CB - Levi Wallace, Taron Johnson | S - Jordan Poyer, Micah Hyde | K - Tyler Bass | P - Matt Haack
Carolina Panthers
QB - Cam Newton | RB - Chuba Hubbard | WR - D.J. Moore, Robby Anderson, Brandon Zylstra | TE - Ian Thomas | OL - Cameron Erving, Michael Jordan, Pat Elflein, John Miller, Taylor Moton
DL - Brian Burns, Phil Hoskins, DaQuan Jones, Morgan Fox | LB - Shaq Thompson, Jermaine Carter Jr., Haason Reddick | CB - Stephon Gilmore, Keith Taylor Jr. | S - Jeremy Chinn, Juston Burris | K - Zane Gonzalez | P - Lachlan Edwards
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