Denver Broncos vs. Buffalo Bills prediction and picks for wild-card round feat. Bo Nix, Josh Allen

Wild Card preview of Broncos vs Bills
Wild Card preview of Broncos vs Bills (image credit: getty)

The wild-card round of the NFL playoffs will feature an AFC matchup between the Buffalo Bills and Denver Broncos. The Bills earned the No. 2 seed after their excellent season, while the Broncos exceeded expectations to get into the postseason with their rookie quarterback. Here's how things could play out in this game.

Denver Broncos vs Buffalo Bills prediction

Josh Allen (image credit: getty)
Josh Allen (image credit: getty)

The Buffalo Bills will host the Denver Broncos in the wild-card round which is a major advantage for them as they finished with a perfect 8-0 record at home. They also avoided going to Denver which is one of the most difficult road environments to play in.

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The Bills will enter this matchup as one of the biggest favorites of the wild-card round, given their strong season, playing at home where they are unbeaten and their lengthy playoff experience in recent years. They have now participated in the postseason in each of the past six years, while the Broncos will be playing in their first playoff game since the 2015 season.

Many factors contribute to why the Bills are massive favorites, as well as being one of the favorites to potentially win a Super Bowl ring. The Broncos would need a huge upset to advance to the next round, which is highly unlikely to happen as they will play on the road.

Denver Broncos vs Buffalo Bills picks

Rookie Bo Nix (image credit: getty)
Rookie Bo Nix (image credit: getty)

The Denver Broncos are led by rookie QB Bo Nix, who turned in a strong season. He helped his team punch its ticket into the playoffs by blowing out the Kansas City Chiefs' backups in Week 18. They needed the victory and Nix got it done, but the playoffs are a whole different game, so it will be interesting to see if he can elevate his game.

He will be rivaled by Josh Allen, who is among the favorites, along with Lamar Jackson, to be named the NFL MVP this year. He is looking for his first MVP award, as well as a deeper playoff run with the Buffalo Bills, including a potential Super Bowl ring.

The predicted outcome is a 28-17 final score.

Buffalo Bills Nation! Check out the latest Buffalo Bills Schedule and dive into the latest Bills Depth Chart for NFL Season 2024-25.

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Edited by Victor Ramon Galvez
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