Prediction
The way I can see the Packers win is if they go up by a touchdown early on and force the Niners to throw the ball. I have talked at length about how Green Bay is too transparent with what they do on defense, so forcing Jimmy G to process a lot of information once the ball is snapped will be key. The entire team was schooled in the first meeting between the two teams and not only should the Packers be more prepared this time around, but they also have the taste of revenge in their mouths.
Having said that, to me the 49ers have been the best team in the AFC for pretty much the entire year now. I trust Shanahan to get the offense moving and if they can control the line of scrimmage with their ground attack, they are almost impossible to beat. It will take a heroic performance by Rodgers to really put up points against this outstanding defense. With their arsenal of pass-rushers and a fully healthy back-seven, I think they are just too much to handle. A late field goal after the Packers fail to convert on fourth down might seal this.
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Green Bay 17-26 San Francisco
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