Kansas City Chiefs vs Buffalo Bills predictions: Picks and odds for AFC championship showdown

The Kansas City Chiefs will host the Buffalo Bills in the second and final matchup of the 2024 Sunday Championship at Arrowhead Stadium. The Chiefs defeated the same opponent at Highmark Stadium last season to advance to the AFC Championship game against the Baltimore Ravens.

Considering the history between these two franchises, this matchup is expected to be a high-flying, hard-fought game that could define history for either team.

Kansas City Chiefs vs Buffalo Bills prediction

The stakes are high for both teams taking the field this Sunday. The Kansas City Chiefs are on a quest to become the first team in NFL history to win three straight championships, while Josh Allen and the Buffalo Bills are keen to dethrone the back-to-back defending champions for the first time in the postseason to advance to the biggest game of all.

Patrick Mahomes hasn't had the most spectacular season, but he's done just enough to lead his squad to this point, which is when they are more dangerous. After an easy win over the Houston Texans, they enter this game as a +2.5 underdog.

The Bills know they have a date with destiny once the game starts, but to make it to the next level, they need to beat the team that has recently ruined their championship plans.

Their regular season meeting in Week 11 ended with a 30-21 win for the Bills at home. However, just as their stadium gave them the edge over the Ravens last week, the Chiefs could be in the same position on Sunday, Jan. 26. This game should be close from start to finish and an instant classic, given everything that's on the line. That said, the Bills should prove that they are ready to get over the hump and reach the Super Bowl in a hostile environment.

Kansas City Chiefs vs Buffalo Bills picks

It's a no-brainer that the two most important players in this Kansas City Chiefs vs. Buffalo Bills matchup are Patrick Mahomes and Josh Allen. The quarterbacks will be tasked with leading their teams to the big game, with both likely needing to post more than the 177 passing yards and single touchdown Mahomes threw against the Texans and the 127 yards Allen threw against the Ravens.

Besides the quarterbacks, players of interest will be Kareem Hunt, who has scored three touchdowns in the last three games, Travis Kelce, and DeAndre Hopkins for the Chiefs. Meanwhile, James Cook and Khalil Shakir are two dangerous weapons for Buffalo.