2021-22 San Francisco 49ers Football Schedule

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2024-25 2023-24 2022-23 2021-22 2020-21

Post Season

WK	DATE	OPPONENT	RESULT	W-L	HI PASS	HI RUSH	HI REC
WC	Sun, 16 Jan	@ Dallas Cowboys	W 23 - 17	0 - 0	Dak Prescott 254	Elijah Mitchell 96	Dalton Schultz 89
DIV	Sat, 22 Jan	@ Green Bay Packers	W 13 - 10	0 - 0	Aaron Rodgers 225	Elijah Mitchell 53	Aaron Jones 129
CONF	Sun, 30 Jan	@ Los Angeles Rams	L 17 - 20	0 - 0	Matthew Stafford 337	Cam Akers 48	Cooper Kupp 142

Regular Season

WK	DATE	OPPONENT	RESULT	W-L	HI PASS	HI RUSH	HI REC
1	Sun, 12 Sep	@ Detroit Lions	W 41 - 33	1 - 0	Jared Goff 338	Elijah Mitchell 104	Deebo Samuel Sr. 189
2	Sun, 19 Sep	@ Philadelphia Eagles	W 17 - 11	2 - 0	Jalen Hurts 190	Jalen Hurts 82	Quez Watkins 117
3	Sun, 26 Sep	vs Green Bay Packers	L 28 - 30	2 - 1	Aaron Rodgers 261	Aaron Jones 82	Davante Adams 132
4	Sun, 03 Oct	vs Seattle Seahawks	L 21 - 28	2 - 2	Jimmy Garoppolo 165	Trey Sermon 89	Deebo Samuel Sr. 156
5	Sun, 10 Oct	@ Arizona Cardinals	L 10 - 17	2 - 3	Kyler Murray 239	Trey Lance 89	DeAndre Hopkins 87
6	BYE WEEK
7	Sun, 24 Oct	vs Indianapolis Colts	L 18 - 30	2 - 4	Jimmy Garoppolo 181	Elijah Mitchell 107	Michael Pittman Jr. 105
8	Sun, 31 Oct	@ Chicago Bears	W 33 - 22	3 - 4	Jimmy Garoppolo 322	Elijah Mitchell 137	Deebo Samuel Sr. 171
9	Sun, 07 Nov	vs Arizona Cardinals	L 17 - 31	3 - 5	Jimmy Garoppolo 326	James Conner 96	George Kittle 101
10	Mon, 15 Nov	vs Los Angeles Rams	W 31 - 10	4 - 5	Matthew Stafford 243	Elijah Mitchell 91	Cooper Kupp 122
11	Sun, 21 Nov	@ Jacksonville Jaguars	W 30 - 10	5 - 5	Jimmy Garoppolo 176	Deebo Samuel Sr. 79	Brandon Aiyuk 85
12	Sun, 28 Nov	vs Minnesota Vikings	W 34 - 26	6 - 5	Kirk Cousins 238	Elijah Mitchell 133	Brandon Aiyuk 91
13	Sun, 05 Dec	@ Seattle Seahawks	L 23 - 30	6 - 6	Jimmy Garoppolo 299	Travis Homer 80	George Kittle 181
14	Sun, 12 Dec	@ Cincinnati Bengals	W 26 - 23	7 - 6	Joe Burrow 348	Joe Mixon 58	George Kittle 151
15	Sun, 19 Dec	vs Atlanta Falcons	W 31 - 13	8 - 6	Matt Ryan 236	Jeff Wilson Jr. 110	George Kittle 93
16	Thu, 23 Dec	@ Tennessee Titans	L 17 - 20	8 - 7	Jimmy Garoppolo 322	Jeff Wilson Jr. 45	Deebo Samuel Sr. 159
17	Sun, 02 Jan	vs Houston Texans	W 23 - 7	9 - 7	Trey Lance 249	Elijah Mitchell 119	Brandon Aiyuk 94
18	Sun, 09 Jan	@ Los Angeles Rams	W 27 - 24	10 - 7	Jimmy Garoppolo 316	Elijah Mitchell 85	Cooper Kupp 118

Pre Season

WK	DATE	OPPONENT	RESULT	W-L	HI PASS	HI RUSH	HI REC
1	Sat, 14 Aug	vs Kansas City Chiefs	L 16 - 19	0 - 1	Trey Lance 128	JaMycal Hasty 63	Trent Sherfield 80
2	Sun, 22 Aug	@ Los Angeles Chargers	W 15 - 10	1 - 1	Trey Lance 102	Wayne Gallman Jr. 72	Trent Sherfield 50
3	Sun, 29 Aug	vs Las Vegas Raiders	W 34 - 10	2 - 1	Nathan Peterman 175	Wayne Gallman Jr. 60	Dillon Stoner 69

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